Astrocyte-Selective Volume Increase in Elevated Extracellular Potassium Conditions Is Mediated by the Na/K ATPase and Occurs Independently of Aquaporin 4

Astrocytes and neurons have been shown to swell across a variety of different conditions, including increases in extracellular potassium concentration (^[K + ] o ). The mechanisms involved in the coupling of K + influx to water movement into cells leading to cell swelling are not well understood and...

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Bibliographic Details
Main Authors: Erin Walch, Thomas R. Murphy, Nicholas Cuvelier, Murad Aldoghmi, Cristine Morozova, Jordan Donohue, Gaby Young, Anuja Samant, Stacy Garcia, Camila Alvarez, Alex Bilas, David Davila, Devin K. Binder, Todd A. Fiacco
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:ASN Neuro
Online Access:https://doi.org/10.1177/1759091420967152