Poly-ubiquitin profile in Alzheimer disease brain

Poly-ubiquitin profile in Alzheimer disease brain

Alzheimer disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory, reasoning and other cognitive functions. Pathologically, patients with AD are characterized by deposition of senile plaques (SPs), formed by β-amyloid (Aβ), and neurofibrillary tangles (NTFs) that con...

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Bibliographic Details
Main Authors: Antonella Tramutola, Francesca Triani, Fabio Di Domenico, Eugenio Barone, Jian Cai, Jon B. Klein, Marzia Perluigi, D. Allan Butterfield
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Neurobiology of Disease
Subjects:
Polyubiquintinylation
Alzheimer disease brain
Proteomics
Contribution to neurodegeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118302110

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http://www.sciencedirect.com/science/article/pii/S0969996118302110

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