Synthesis, Molecular Docking and In Vitro Screening of Some Newly Synthesized Triazolopyridine, Pyridotriazine and Pyridine–Pyrazole Hybrid Derivatives

Synthesis, Molecular Docking and In Vitro Screening of Some Newly Synthesized Triazolopyridine, Pyridotriazine and Pyridine–Pyrazole Hybrid Derivatives

A series of novel pyridine and fused pyridine derivatives have been prepared starting from 6-(3,4-dimethylphenyl)-2-hydrazinyl-4-(thiophen-2-yl)-pyridine-3-carbonitrile 1 which on treatment with appropriate formic acid, acetic acid/acetic anhydride, benzoyl chloride and/or carbon disulfide afforded...

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Bibliographic Details
Main Authors: Eman M. Flefel, Walaa I. El-Sofany, Mahmoud El-Shahat, Arshi Naqvi, Eman Assirey
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
triazolopyridine
pyridotriazine
pyridine–pyrazole hybrids
antimicrobial activity
antioxidant agent
in silico molecular docking
Online Access:http://www.mdpi.com/1420-3049/23/10/2548

Internet

http://www.mdpi.com/1420-3049/23/10/2548

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