The influence of microRNAs and poly(A) tail length on endogenous mRNA–protein complexes

The influence of microRNAs and poly(A) tail length on endogenous mRNA–protein complexes

Abstract Background All mRNAs are bound in vivo by proteins to form mRNA–protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have analyzed, on a transcriptome-wide scale, how microRNA-mediated repression modulat...

Full description

Bibliographic Details
Main Authors: Olivia S. Rissland, Alexander O. Subtelny, Miranda Wang, Andrew Lugowski, Beth Nicholson, John D. Laver, Sachdev S. Sidhu, Craig A. Smibert, Howard D. Lipshitz, David P. Bartel
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Genome Biology
Subjects:
MicroRNAs
Poly(A) tail
mRNA–protein complexes
Online Access:http://link.springer.com/article/10.1186/s13059-017-1330-z

Internet

http://link.springer.com/article/10.1186/s13059-017-1330-z

Similar Items