A novel Drosophila injury model reveals severed axons are cleared through a Draper/MMP-1 signaling cascade

Neural injury triggers swift responses from glia, including glial migration and phagocytic clearance of damaged neurons. The transcriptional programs governing these complex innate glial immune responses are still unclear. Here, we describe a novel injury assay in adult Drosophila that elicits wides...

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Bibliographic Details
Main Authors: Maria D Purice, Arpita Ray, Eva Jolanda Münzel, Bernard J Pope, Daniel J Park, Sean D Speese, Mary A Logan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/23611