Sevoflurane Inhibition of the Slowly Activating Delayed Rectifier K+ Current in Guinea Pig Ventricular Cells
Single ventricular cells were enzymatically isolated from guinea pig hearts and the effects of sevoflurane on the delayed rectifier K+ current were investigated by the patch clamp method. The rapidly (IKr) and slowly activating delayed rectifier K+ current (IKs) were isolated using chromanol 293B, a...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2004-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S134786131932417X |