Reduced CSF turnover and decreased ventricular Aβ42 levels are related

<p>Abstract</p> <p>Background</p> <p>The appearance of Aβ42 peptide deposits is admitted to be a key event in the pathogenesis of Alzheimer's disease, although amyloid deposits also occur in aged non-demented subjects. Aβ42 is a degradation product of the amyloid p...

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Bibliographic Details
Main Authors: Jouanny Pierre, Bourgeois Anne-Marie, Ledeme Nelly, Fichten Antony, Peltier Johann, Serot Jean-Marie, Toussaint Patrick, Legars Daniel, Godefroy Olivier, Mazière Jean-Claude
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/12/42