Genes Regulated by Vitamin D in Bone Cells Are Positively Selected in East Asians.

Vitamin D and folate are activated and degraded by sunlight, respectively, and the physiological processes they control are likely to have been targets of selection as humans expanded from Africa into Eurasia. We investigated signals of positive selection in gene sets involved in the metabolism, reg...

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Bibliographic Details
Main Authors: Elena Arciero, Simone Andrea Biagini, Yuan Chen, Yali Xue, Donata Luiselli, Chris Tyler-Smith, Luca Pagani, Qasim Ayub
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4697808?pdf=render