Immune responses to epidermal growth factor receptor (EGFR) and their application for cancer treatment

Epidermal growth factor receptor (EGFR) is a prototypic cell-surface receptor belonging to the ErbB/HER onocogene family. Overexpression or somatic mutations of EGFR have been reported to play an important role in tumorigenesis in various types of epithelial cancers. Therefore, targeting of EGFR wit...

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Bibliographic Details
Main Authors: Tetsuro Sasada, Koichi Azuma, Junya Ohtake, Yuki Fujimoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00405/full