Clinical heterogeneity of duchenne muscular dystrophy (DMD): definition of sub-phenotypes and predictive criteria by long-term follow-up.

BACKGROUND: To explore clinical heterogeneity of Duchenne muscular dystrophy (DMD), viewed as a major obstacle to the interpretation of therapeutic trials METHODOLOGY/PRINCIPAL FINDINGS: A retrospective single institution long-term follow-up study was carried out in DMD patients with both complete l...

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Bibliographic Details
Main Authors: Isabelle Desguerre, Christo Christov, Michele Mayer, Reinhard Zeller, Henri-Marc Becane, Sylvie Bastuji-Garin, France Leturcq, Catherine Chiron, Jamel Chelly, Romain K Gherardi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2633042?pdf=render