Warfarin administration reduces synthesis of sulfatides and other sphingolipids in mouse brain

The modulation of phosphosphingolipid synthesis by vitamin K depletion has been observed in the vitamin K-dependent microorganism, Bacteriodes levii. When cultured briefly without the vitamin, a reduction occurred in the activity of the first enzyme of the sphingolipid pathway, 3-ketodihydrosphingos...

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Bibliographic Details
Main Authors: K S Sundaram, M Lev
Format: Article
Language:English
Published: Elsevier 1988-11-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520384261