DNA hypomethylation of the COX-2 gene promoter is associated with up-regulation of its mRNA expression in eutopic endometrium of endometriosis

<p>Abstract</p> <p>Background</p> <p>Accumulated evidence reveals that cyclooxygenase-2 (COX-2) was overexpressed in eutopic endometrium of endometriosis, which may play a critical role in the pathogenesis of endometriosis. However, few studies have been performed to ex...

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Bibliographic Details
Main Authors: Wang DanBo, Chen Qi, Zhang ChiYuan, Ren Fang, Li Tong
Format: Article
Language:English
Published: BMC 2012-05-01
Series:European Journal of Medical Research
Subjects:
Online Access:http://www.eurjmedres.com/content/17/1/12