Role of Polycomb Group Protein Cbx2/M33 in Meiosis Onset and Maintenance of Chromosome Stability in the Mammalian Germline

Role of Polycomb Group Protein Cbx2/M33 in Meiosis Onset and Maintenance of Chromosome Stability in the Mammalian Germline

Polycomb group proteins (PcG) are major epigenetic regulators, essential for establishing heritable expression patterns of developmental control genes. The mouse PcG family member M33/Cbx2 (Chromobox homolog protein 2) is a component of the Polycomb-Repressive Complex 1 (PRC1). Targeted deletion of...

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Bibliographic Details
Main Authors: Claudia Baumann, Rabindranath De La Fuente
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Genes
Subjects:
oogenesis
pericentric heterochromatin
epigenetic modifications
chromatin remodeling
retinoic acid
sex determination
Online Access:http://www.mdpi.com/2073-4425/2/1/59/

Internet

http://www.mdpi.com/2073-4425/2/1/59/

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