Evidence for transgenerational transmission of epigenetic tumor susceptibility in Drosophila.

Transgenerational epigenetic inheritance results from incomplete erasure of parental epigenetic marks during epigenetic reprogramming at fertilization. The significance of this phenomenon, and the mechanism by which it occurs, remains obscure. Here, we show that genetic mutations in Drosophila may c...

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Bibliographic Details
Main Authors: Yalan Xing, Song Shi, Long Le, Crystal A Lee, Louise Silver-Morse, Willis X Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1971119?pdf=render