ST2 and regulatory T cells in the colorectal adenoma/carcinoma microenvironment: implications for diseases progression and prognosis

Abstract ST2 (also known as IL1RL1) is the critical functional receptor for interleukin (IL)-33 in stimulating regulatory T cell (Treg) expansion and function in physiological and pathological conditions. We examined the correlation between ST2 cell expression and FoxP3 positive Tregs in both colore...

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Bibliographic Details
Main Authors: Guanglin Cui, Aping Yuan, Zhenfeng Li, Rasmus Goll, Jon Florholmen
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-62502-0