Postoperative hepatic arterial chemotherapy in high-risk patients as adjuvant treatment after resection of colorectal liver metastases - a randomized phase II/III trial – PACHA-01 (NCT02494973)

Postoperative hepatic arterial chemotherapy in high-risk patients as adjuvant treatment after resection of colorectal liver metastases - a randomized phase II/III trial – PACHA-01 (NCT02494973)

Abstract Background After curative-intent surgery for colorectal liver metastases (CRLM), liver recurrence occurs in more than 60% of patients, despite the administration of perioperative or adjuvant chemotherapy. This risk is even higher after resection of more than three CRLM. As CRLM are mostly s...

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Bibliographic Details
Main Authors: Diane Goéré, Jean-Pierre Pignon, Maximiliano Gelli, Dominique Elias, Léonor Benhaim, Frédéric Deschamps, Caroline Caramella, Valérie Boige, Michel Ducreux, Thierry de Baere, David Malka
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Cancer
Subjects:
Colorectal cancer
Liver metastases
Liver resection
Adjuvant chemotherapy
Hepatic arterial infusion
Oxaliplatin
Online Access:http://link.springer.com/article/10.1186/s12885-018-4697-7

Internet

http://link.springer.com/article/10.1186/s12885-018-4697-7

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