Preclinical platform for long-term evaluation of immuno-oncology drugs using hCD34+ humanized mouse model

Preclinical platform for long-term evaluation of immuno-oncology drugs using hCD34+ humanized mouse model

Background Well-characterized preclinical models are essential for immune-oncology research. We investigated the feasibility of our humanized mouse model for evaluating the long-term efficacy of immunotherapy and biomarkers.Methods Humanized mice were generated by injecting human fetal cord blood-de...

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Bibliographic Details
Main Authors: Yong Wha Moon, Nahee Park, Kamal Pandey, Sei Kyung Chang, Ah-Young Kwon, Young Bin Cho, Jin Hur, Nar Bahadur Katwal, Seung Ki Kim, Seung Ah Lee, Gun Woo Son, Jong Min Jo, Hee Jung Ahn
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e001513.full

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https://jitc.bmj.com/content/8/2/e001513.full

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