Defining the role of fluid shear stress in the expression of early signaling markers for calcific aortic valve disease.

Calcific aortic valve disease (CAVD) is an active process presumably triggered by interplays between cardiovascular risk factors, molecular signaling networks and hemodynamic cues. While earlier studies demonstrated that alterations in fluid shear stress (FSS) on the fibrosa could trigger inflammati...

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Bibliographic Details
Main Authors: Ling Sun, Nalini M Rajamannan, Philippe Sucosky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24376809/pdf/?tool=EBI