The Coronavirus PEDV Evades Type III Interferon Response Through the miR-30c-5p/SOCS1 Axis

The Coronavirus PEDV Evades Type III Interferon Response Through the miR-30c-5p/SOCS1 Axis

Porcine epidemic diarrhea virus (PEDV) is an economically important pathogen that has evolved several mechanisms to evade type I IFN responses. Type III interferon (IFN-λ), an innate cytokine that primarily targets the mucosal epithelia, is critical in fighting mucosal infection in the host and has...

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Bibliographic Details
Main Authors: Changlin Wang, Lingling Shan, Shuxin Qu, Mei Xue, Keliang Wang, Fang Fu, Lu Wang, Ziqi Wang, Li Feng, Wanhai Xu, Pinghuang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Microbiology
Subjects:
coronavirus
PEDV
IFN-λ
SOCS1
microRNA
miR-30c-5p
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01180/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01180/full

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