Critical role of non-muscle myosin light chain kinase in thrombin-induced endothelial cell inflammation and lung PMN infiltration.

Critical role of non-muscle myosin light chain kinase in thrombin-induced endothelial cell inflammation and lung PMN infiltration.

The pathogenesis of acute lung injury (ALI) involves bidirectional cooperation and close interaction between inflammatory and coagulation pathways. A key molecule linking coagulation and inflammation is the procoagulant thrombin, a serine protease whose concentration is elevated in plasma and lavage...

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Bibliographic Details
Main Authors: Fabeha Fazal, Kaiser M Bijli, Matthew Murrill, Antony Leonard, Mohammad Minhajuddin, Khandaker N Anwar, Jacob N Finkelstein, D Martin Watterson, Arshad Rahman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3605402?pdf=render

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http://europepmc.org/articles/PMC3605402?pdf=render

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