T Helper Lymphocyte Subsets and Plasticity in Autoimmunity and Cancer: An Overview

In response to cytokine signalling and other factors, CD4-positive T lymphocytes differentiate into distinct populations that are characterized by the production of certain cytokines and are controlled by different master transcription factors. The spectrum of such populations, which was initially l...

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Bibliographic Details
Main Authors: Ekaterina A. Ivanova, Alexander N. Orekhov
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/327470