High-dose enalapril treatment reverses myocardial fibrosis in experimental uremic cardiomyopathy.

AIMS: Patients with renal failure develop cardiovascular alterations which contribute to the higher rate of cardiac death. Blockade of the renin angiotensin system ameliorates the development of such changes. It is unclear, however, to what extent ACE-inhibitors can also reverse existing cardiovascu...

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Bibliographic Details
Main Authors: Karin Tyralla, Marcin Adamczak, Kerstin Benz, Valentina Campean, Marie-Luise Gross, Karl F Hilgers, Eberhard Ritz, Kerstin Amann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3029304?pdf=render