GPR41 and GPR43¬ in obesity and inflammation – protective or causative?

GPR41 and GPR43 are a pair of mammalian G-protein coupled receptors (GPCRs) expressed in human adipocytes, colon epithelial cells and peripheral blood mononuclear cells. These receptors are activated by short-chain fatty acids (SCFAs) such as acetate, propionate and butyrate– which are produced duri...

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Bibliographic Details
Main Authors: Zhiwei eAng, Jeak Ling eDing
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00028/full