Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice

<p>Abstract</p> <p>Background</p> <p>The purpose of this study was to investigate whether localized peripheral inflammation, such as osteoarthritis, contributes to neuroinflammation and neurodegenerative disease <it>in vivo</it>.</p> <p>Methods&l...

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Bibliographic Details
Main Authors: Yang Meixiang, Johnson Renee, Olschowka Mallory E, Miller Jen-nie H, Tallents Ross H, Kyrkanides Stephanos, Olschowka John A, Brouxhon Sabine M, O'Banion M Kerry
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/112