Cell-Penetrating Peptides: Design Strategies beyond Primary Structure and Amphipathicity

Efficient intracellular drug delivery and target specificity are often hampered by the presence of biological barriers. Thus, compounds that efficiently cross cell membranes are the key to improving the therapeutic value and on-target specificity of non-permeable drugs. The discovery of cell-penetra...

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Bibliographic Details
Main Authors: Daniela Kalafatovic, Ernest Giralt
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/22/11/1929