Grape pomace enzymatic extract restores vascular dysfunction evoked by endothelin-1 and DETCA via NADPH oxidase downregulation and SOD activation

Grape pomace enzymatic extract restores vascular dysfunction evoked by endothelin-1 and DETCA via NADPH oxidase downregulation and SOD activation

Grape pomace enzymatic extract (GP-EE) exhibits a potent antioxidant and vasodilator activity, although the mechanisms underlying this action are not completely understood. Our aim was to evaluate its vasoactive mechanisms, focusing on vascular NADPH oxidase and superoxide dismutase (SOD)-dependent...

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Bibliographic Details
Main Authors: Cristina Perez-Ternero, Rosalia Rodriguez-Rodriguez, Juan Parrado, Maria Alvarez de Sotomayor
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Journal of Functional Foods
Subjects:
Grape pomace
Catechin
Epicatechin
Superoxide dismutase
NADPH oxidase
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464613001758

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http://www.sciencedirect.com/science/article/pii/S1756464613001758

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