How do multi-stage, multi-arm trials compare to the traditional two-arm parallel group design – a reanalysis of 4 trials

<p>Abstract</p> <p>Background</p> <p>To speed up the evaluation of new therapies, the multi-arm, multi-stage trial design was suggested previously by the authors.</p> <p>Methods</p> <p>In this paper, we evaluate the performance of the two-stage,...

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Bibliographic Details
Main Authors: Barthel FM-S, Parmar MKB, Royston P
Format: Article
Language:English
Published: BMC 2009-04-01
Series:Trials
Online Access:http://www.trialsjournal.com/content/10/1/21