Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer’s Disease

Brain capillary endothelial cells form the blood-brain barrier (BBB), which is covered with basement membranes and is also surrounded by pericytes and astrocyte end-feet in the neurovascular unit. The BBB tightly regulates the molecular exchange between the blood flow and brain parenchyma, thereby r...

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Bibliographic Details
Main Authors: Yu Yamazaki, Takahisa Kanekiyo
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/18/9/1965