The Severity of Visceral Leishmaniasis Correlates with Elevated Levels of Serum IL-6, IL-27 and sCD14.

BACKGROUND:Visceral leishmaniasis (VL) is a severe disease caused by infection with protozoa of the genus Leishmania. Classic VL is characterized by a systemic infection of phagocytic cells and an intense activation of the inflammatory response. It is unclear why 90% of infected individuals do not d...

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Main Authors: Priscila L Dos Santos, Fabrícia A de Oliveira, Micheli Luize B Santos, Luana Celina S Cunha, Michelle T B Lino, Michelle F S de Oliveira, Manuela O M Bomfim, Angela Maria Silva, Tatiana R de Moura, Amélia R de Jesus, Malcolm S Duthie, Steven G Reed, Roque P de Almeida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4729473?pdf=render