Mouse models and the interpretation of human GWAS in type 2 diabetes and obesity
Within the last 3 years, genome-wide association studies (GWAS) have had unprecedented success in identifying loci that are involved in common diseases. For example, more than 35 susceptibility loci have been identified for type 2 diabetes and 32 for obesity thus far. However, the causal gene and va...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2011-03-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/4/2/155 |