Genomic amplification of chromosome 20q13.33 is the early biomarker for the development of sporadic colorectal carcinoma

Genomic amplification of chromosome 20q13.33 is the early biomarker for the development of sporadic colorectal carcinoma

Abstract Background Colorectal carcinoma (CRC) is the third most common cancer in the world and also the third leading cause of cancer-related mortality in Taiwan. CRC tumorigenesis is a multistep process, starting from mutations causing loss of function of tumor suppressor genes, canonically demons...

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Bibliographic Details
Main Authors: Vo-Minh-Hoang Bui, Clément Mettling, Jonathan Jou, H. Sunny Sun
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Medical Genomics
Subjects:
Chromosome instability
Microsatellite instability
Biomarker
Sporadic CRC
Adenoma – carcinoma process
Online Access:http://link.springer.com/article/10.1186/s12920-020-00776-z

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http://link.springer.com/article/10.1186/s12920-020-00776-z

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