The presence of genetic risk variants within PTPN2 and PTPN22 is associated with intestinal microbiota alterations in Swiss IBD cohort patients.

The presence of genetic risk variants within PTPN2 and PTPN22 is associated with intestinal microbiota alterations in Swiss IBD cohort patients.

BACKGROUND:Genetic risk factors, intestinal microbiota and a dysregulated immune system contribute to the pathogenesis of inflammatory bowel disease (IBD). We have previously demonstrated that dysfunction of protein tyrosine phosphatase non-receptor type 2 (PTPN2) and PTPN22 contributes to alteratio...

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Bibliographic Details
Main Authors: Bahtiyar Yilmaz, Marianne R Spalinger, Luc Biedermann, Yannick Franc, Nicolas Fournier, Jean-Benoit Rossel, Pascal Juillerat, Gerhard Rogler, Andrew J Macpherson, Michael Scharl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6028086?pdf=render

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http://europepmc.org/articles/PMC6028086?pdf=render

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