Heme-oxygenases during erythropoiesis in K562 and human bone marrow cells.

In mammalian cells, heme can be degraded by heme-oxygenases (HO). Heme-oxygenase 1 (HO-1) is known to be the heme inducible isoform, whereas heme-oxygenase 2 (HO-2) is the constitutive enzyme. Here we investigated the presence of HO during erythroid differentiation in human bone marrow erythroid pre...

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Bibliographic Details
Main Authors: Liliane R Alves, Elaine S Costa, Marcos H F Sorgine, Maria Clara L Nascimento-Silva, Cristina Teodosio, Paloma Bárcena, Hugo C Castro-Faria-Neto, Patrícia T Bozza, Alberto Orfao, Pedro L Oliveira, Clarissa M Maya-Monteiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3135583?pdf=render