Pre-operative denosumab is associated with higher risk of local recurrence in giant cell tumor of bone: a systematic review and meta-analysis

Abstract Background In 2013, denosumab was introduced as peri-operative adjuvant treatment for giant cell tumor (GCT) of bone as it inhibits osteoclast activity. It is suggested that denosumab relives pain, facilitate curettage in lesions requiring resection initially. However, controversy remains w...

Full description

Bibliographic Details
Main Authors: Xi Chen, Hairui Li, Shibai Zhu, Yiou Wang, Wenwei Qian
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12891-020-03294-2