Calreticulin Release at an Early Stage of Death Modulates the Clearance by Macrophages of Apoptotic Cells

Calreticulin (CRT) is a well-known “eat-me” signal harbored by dying cells participating in their recognition by phagocytes. CRT is also recognized to deeply impact the immune response to altered self-cells. In this study, we focus on the role of the newly exposed CRT following cell death induction....

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Bibliographic Details
Main Authors: Rim Osman, Pascale Tacnet-Delorme, Jean-Philippe Kleman, Arnaud Millet, Philippe Frachet
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
C1q
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01034/full