Identification of Cells Expressing Cyclooxygenase-2 in Response to Interleukin-1β in Rat Aortae

Localization of cyclooxygenase-2 (COX-2) in rat aortae was investigated. In endothelium-intact aortic strips stimulated with interleukin-1 β (IL-1 β ), COX-2 was detected in adventitial fibroblasts and macrophages but not in tunica media. IL-1 β−induced COX-2 expression was also detected in medial s...

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Bibliographic Details
Main Authors: Tomoyuki Nakano, Ichiro Wakabayashi
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319309648