Shaping of Natural Killer Cell Antitumor Activity by Ex Vivo Cultivation

Natural killer (NK) cells are a promising tool for the use in adoptive immunotherapy, since they efficiently recognize and kill tumor cells. In this context, ex vivo cultivation is an attractive option to increase NK cells in numbers and to improve their antitumor potential prior to clinical applica...

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Bibliographic Details
Main Authors: Markus Granzin, Evelyn Ullrich, Juliane Wagner, Ulrike Köhl, Adelheid Cerwenka, Volker Huppert
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00458/full