Parallel Evolution of Tobramycin Resistance across Species and Environments

The rise of antimicrobial resistance is a leading medical threat, motivating efforts to forecast both its evolutionary dynamics and its genetic causes. Aminoglycosides are a major class of antibiotics that disrupt translation, but resistance may occur by a number of mechanisms. Here, we show the rep...

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Bibliographic Details
Main Authors: Michelle R. Scribner, Alfonso Santos-Lopez, Christopher W. Marshall, Christopher Deitrick, Vaughn S. Cooper
Format: Article
Language:English
Published: American Society for Microbiology 2020-05-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.00932-20