Targeting Costimulatory Pathways in Systemic Sclerosis

Targeting Costimulatory Pathways in Systemic Sclerosis

Systemic sclerosis (SSc) is an autoimmune T-cell disease that is characterized by pathological fibrosis of the skin and internal organs. SSc is considered a prototype condition for studying the links between autoimmunity and fibrosis. Costimulatory pathways such as CD28/CTLA-4, ICOS-B7RP1, CD70-CD27...

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Bibliographic Details
Main Authors: Gonçalo Boleto, Yannick Allanore, Jérôme Avouac
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
adaptive immunity
inflammation
costimulatory pathways
systemic sclerosis
fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02998/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02998/full

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