Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells

Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells

Abstract Background Long Interspersed Nuclear Element-1 (LINE-1) is an autonomous retrotransposon that generates new genomic insertions through the retrotransposition of a RNA intermediate. Expression of LINE-1 is tightly repressed in most somatic tissues to prevent DNA damage and ensure genomic int...

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Bibliographic Details
Main Authors: Erica M. Briggs, Susan Ha, Paolo Mita, Gregory Brittingham, Ilaria Sciamanna, Corrado Spadafora, Susan K. Logan
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Mobile DNA
Subjects:
Transposable element
Prostate cancer
Tumor cell biology
Protein expression
Fluorescence
LINE-1
Online Access:http://link.springer.com/article/10.1186/s13100-017-0106-z

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http://link.springer.com/article/10.1186/s13100-017-0106-z

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