Expression profiling of WD40 family genes including DDB1- and CUL4- associated factor (DCAF) genes in mice and human suggests important regulatory roles in testicular development and spermatogenesis

Expression profiling of WD40 family genes including DDB1- and CUL4- associated factor (DCAF) genes in mice and human suggests important regulatory roles in testicular development and spermatogenesis

Abstract Background The WD40-repeat containing proteins, including DDB1–CUL4-associated factors (DCAFs), are abundant and conserved proteins that play important roles in different cellular processes including spermatogenesis. DCAFs are subset of WD40 family proteins that contain WDxR motif and have...

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Bibliographic Details
Main Authors: Bhavesh V. Mistry, Maha Alanazi, Hanae Fitwi, Olfat Al-Harazi, Mohamed Rajab, Abdullah Altorbag, Falah Almohanna, Dilek Colak, Abdullah M. Assiri
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Genomics
Subjects:
WD40-repeat
DDB1–CUL4-associated factors
Gene expression
RNA sequencing
Testis
Ubiquitination
Online Access:http://link.springer.com/article/10.1186/s12864-020-07016-9

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http://link.springer.com/article/10.1186/s12864-020-07016-9

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