Anti-Ly6G binding and trafficking mediate positive neutrophil selection to unleash the anti-tumor efficacy of radiation therapy

Anti-Ly6G binding and trafficking mediate positive neutrophil selection to unleash the anti-tumor efficacy of radiation therapy

The anti-Ly6G antibody is used to deplete Ly6Gpos neutrophils and study their role in diverse pathologies. However, depletion is never absolute, as Ly6Glow neutrophils resistant to depletion rapidly emerge. Studying the functionality of these residual neutrophils is necessary to interpret anti-Ly6G-...

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Bibliographic Details
Main Authors: Gaël Boivin, Pierre-Benoit Ancey, Romain Vuillefroy de Silly, Pradeep Kalambaden, Caroline Contat, Benoit Petit, Jonathan Ollivier, Jean Bourhis, Etienne Meylan, Marie-Catherine Vozenin
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
anti-neutrophil cytoplasmic antibody (anca)
depletion resistance
tumor-associated-neutrophils (tans) polarization
radio-sensitization
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1876597

Internet

http://dx.doi.org/10.1080/2162402X.2021.1876597

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