MicroRNA-378 Suppressed Osteogenesis of MSCs and Impaired Bone Formation via Inactivating Wnt/β-Catenin Signaling

MicroRNA-378 Suppressed Osteogenesis of MSCs and Impaired Bone Formation via Inactivating Wnt/β-Catenin Signaling

MicroRNAs (miRNAs) have been reported to serve as silencers to repress gene expression at post-transcriptional levels. Multiple miRNAs have been demonstrated to play important roles in osteogenesis. MicroRNA (miR)-378, a conserved miRNA, was reported to mediate bone metabolism and influence bone dev...

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Bibliographic Details
Main Authors: Lu Feng, Jin-fang Zhang, Liu Shi, Zheng-meng Yang, Tian-yi Wu, Hai-xing Wang, Wei-ping Lin, Ying-fei Lu, Jessica Hiu Tung Lo, Da-hai Zhu, Gang Li
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
miR-378
mesenchymal stem cells
osteogenesis
Wnt/β-catenin signaling
bone formation
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120302079

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http://www.sciencedirect.com/science/article/pii/S2162253120302079

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