Profiling of the germline mutation BRCA1: p.Ile1845fs in a large cohort of Han Chinese breast cancer

Profiling of the germline mutation BRCA1: p.Ile1845fs in a large cohort of Han Chinese breast cancer

Abstract Background Breast cancer is a one of the malignant carcinomas partially caused by genetic risk factors. Germline BRCA1 gene mutations are reportedly associated with breast cancers. Identification of BRCA1 mutations greatly improves the preventive strategies and management of breast cancer....

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Bibliographic Details
Main Authors: Yu Wu, Huanhuan Zhang, Xiaoling Weng, Honglian Wang, Qinghua Zhou, Ying Wu, Yi Shen, Zhen Hu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Hereditas
Subjects:
Breast cancer
BRCA1
P.Ile1845fs
Clinicopathological
Online Access:https://doi.org/10.1186/s41065-019-0115-7

Internet

https://doi.org/10.1186/s41065-019-0115-7

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