Variation in proviral content among human genomes mediated by LTR recombination

Variation in proviral content among human genomes mediated by LTR recombination

Abstract Background Human endogenous retroviruses (HERVs) occupy a substantial fraction of the genome and impact cellular function with both beneficial and deleterious consequences. The vast majority of HERV sequences descend from ancient retroviral families no longer capable of infection or genomic...

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Bibliographic Details
Main Authors: Jainy Thomas, Hervé Perron, Cédric Feschotte
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Mobile DNA
Subjects:
Endogenous retrovirus
HERV-H
HERV-W
HERV-K
Transposable elements
Long terminal repeats
Online Access:http://link.springer.com/article/10.1186/s13100-018-0142-3

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