Variation in proviral content among human genomes mediated by LTR recombination
Abstract Background Human endogenous retroviruses (HERVs) occupy a substantial fraction of the genome and impact cellular function with both beneficial and deleterious consequences. The vast majority of HERV sequences descend from ancient retroviral families no longer capable of infection or genomic...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-12-01
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Series: | Mobile DNA |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13100-018-0142-3 |