Structure of natural variant transglutaminase 2 reveals molecular basis of gaining stability and higher activity.

Multi-functional transglutaminase 2 (TG2), which possesses protein cross-linking and GTP hydrolysis activities, is involved in various cellular processes, including apoptosis, angiogenesis, wound healing, and neuronal regeneration, and is associated with many human diseases, including inflammatory d...

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Bibliographic Details
Main Authors: Hyun Ji Ha, Sunghark Kwon, Eui Man Jeong, Chang Min Kim, Ki Baek Lee, In-Gyu Kim, Hyun Ho Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6188745?pdf=render