Biochemical diversity in the Trypanosoma congolense trans-sialidase family.

Trans-sialidases are key enzymes in the life cycle of African trypanosomes in both, mammalian host and insect vector and have been associated with the disease trypanosomiasis, namely sleeping sickness and nagana. Besides the previously reported TconTS1, we have identified three additional active tra...

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Bibliographic Details
Main Authors: Thaddeus T Gbem, Mario Waespy, Bettina Hesse, Frank Dietz, Joel Smith, Gloria D Chechet, Jonathan A Nok, Sørge Kelm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3855035?pdf=render