Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose

Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose

Background and Purpose: Epidemiological data suggests an excess risk of cardiovascular disease (CVD) at low doses (0.05 and 0.1 Gy) of ionizing radiation (IR). Furthermore, the underlying biological and molecular mechanisms of radiation-induced CVD are still unclear. Because damage to the endotheliu...

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Bibliographic Details
Main Authors: An Aerts, Bjorn Baselet, Niels Belmans, Emma Coninx, Donna Lowe, Ann Janssen, Arlette Michaux, Kevin Tabury, Kenneth Raj, Roel Quintens, Mohammed A. Benotmane, Sarah Baatout, Pierre Sonveaux
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Pharmacology
Subjects:
X-ray
endothelium
atherosclerosis
cardiovascular disease
cell cycle
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00213/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00213/full

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