Genistein upregulates LDLR levels via JNK-mediated activation of SREBP-2
Background: Genistein has been proved in vitro and in vivo to lower LDLR level. It is also widely consumed and implicated for its anti-atherogenic effects. However, the molecular mechanism by which genistein lowers the LDL level is still unknown. Objective: To understand the anti-atherogenic molecul...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Swedish Nutrition Foundation
2016-05-01
|
Series: | Food & Nutrition Research |
Subjects: | |
Online Access: | http://www.foodandnutritionresearch.net/index.php/fnr/article/view/31120/46756 |